What happened in the clinical evaluation?

Clinical Experiences With R1 And R2 for Prophylaxis Of Radiation Dermatitis In Cancer Patients


Acute radiation dermatitis (ARD) occurs in nearly 95 % of all patients receiving radiation therapy in the head and neck area. Currently, there are no evidence-based regimens for prophylaxis of radiation dermatitis
or any standardized treatment recommendations. “R1 and R2” is a novel lactokine-based Class I Medical Device consisting of R1, a water-based gel which offers intense hydration to the skin while providing cooling relief and protecting skin against irritation, and R2, a soothing and moisturising lotion which has high UVB and UVA defense.


Our case series reveals that the application of R1 and R2 is feasible, safe and effective for prophylaxis and for treatment of acute radiation dermatitis. Patients do much better during radiation. They have a better quality of life.

Before treatment with R1 R2

Before treatment with R1 R2

After 16 days of treatment

After 16 days of treatment

Further studies

Attached are further studies into the effectiveness of R1 & R2 as a treatment for skin during and after radiotherapy treatment. The documents are in PDF format.

To best view the studies, we recommend downloading the PDF file to your computer. To do this, right click on the document, or ctrl-click if using a Mac. When the submenu opens, select “Save as. . . ” The file will be stored at the destination you select. Alternatively, left click on each study and it will open in your internet browser window.


Spanish Published Clinical Trial
[June 2015 (148 KB – English)

South Florida Radiation Oncology Hospital Review
[Nov 2012] (148 KB – English)

First clinical Experiences – Heidelberg University Hospital, Germany
[June 2011] (361 KB – English)

University Hospital Heidelberg Germany
[June 2011] (88 KB – English)

Oslo University Hospital, Norway
[June 2011] (392 KB – English)

Fakultni Nemocnice Ostrava, Czech Republic
[May 31st, 2010] (148 KB – English)

You can read what patients say about their experience on our:

Testimonials page